Tim Keller’s conclusion of his “Cosmic Welcome Mat” design argument is:
It is technically possible that we just happened to be in the one universe in which organic life occurred. Though you could not prove that the fine-tuning of the universe was due to some sort of design, it would be unreasonable to draw the conclusion that it wasn’t. Although organic life could have just happened without a Creator, does it make sense to live as if that infinitely remote chance is true? Timothy Keller, The Reason for God, pp. 131-132.
Even though he does not address the origin of life problem directly, he hints at it here. He correctly suggests that the origin of life and the fine-tuning of the universe are all part of the same design inference. There are lots of design clues in the universe. Taken to together, they are very persuasive.